| Cassy T. | Blurry vision after cataract surgery. | case | Orakle LLC | Z Li, OD | ||
| Daniel M. | 43-year-old man with a 20-year history of HIV-1 and persistent viremia despite multiple prior regimens. | case | Orakle LLC | Nada Amgad MD | ||
| Michael R. | 68-year-old man on daily oral HIV PrEP, where repeated HIV antigen/antibody tests are reactive, but confirmatory viral load testing remained undetectable. | case | Orakle LLC | Nada Amgad MD | ||
| Alona K. | A Young Woman Presenting With Headaches and Peripheral Vision Changes | case | Orakle LLC | T. Nakamora MD | ||
| Laura W. | Laura presents with a persistent headache, blurred vision, nausea, vomiting, general malaise, and blood pressure recorded at 230/140 mmHg. | case | Alexion, AstraZeneca Rare Disease | Teresa Cavero Escribano, MD | ||
| Webinar | Webinar: Reflections and learnings from the early gene therapies for Hemophilia B. 2025. | webinar | CSL Behring | Wolfgang Miesbach MD, Amit Nathwani MD, Frank Leebeek MD and Robert Klamroth MD | ||
| Mariam F. | A 14-year-old girl presents with joint pain, fatigue, muscle weakness, and social withdrawal. 0.50 AMA PRA Category 1 Credit(s)™ | case | Alexion, AstraZeneca Rare Disease | Raja Padidela MD and Rachel Lombardo MD | ||
| Mario M. | A 4-year-old presents with diffuse musculoskeletal pain and difficulty keeping up with peers. 0.50 AMA PRA Category 1 Credit(s)™ | case | Alexion, AstraZeneca Rare Disease | Raja Padidela MD and Rachel Lombardo MD | ||
| Rima A. | A 59-year-old woman with end-stage renal disease secondary to atypical hemolytic uremic syndrome has identified a kidney donor and presents today to evaluate her risk of aHUS re... | case | Alexion, AstraZeneca Rare Disease | Veronica Lopez MD | ||
| Amanda S. | Amanda presents with recurrent headaches, hypertension, and worsening renal function four months after breast implantation. | case | Alexion, AstraZeneca Rare Disease | Gustavo Ferreira Da Mata, MD | ||
| Daniel T. | A 56-year-old presents with recurrent non-traumatic fractures, chronic fatigue, and foot pain. 0.50 AMA PRA Category 1 Credit(s)™ | case | Alexion, AstraZeneca Rare Disease | Steven Petak MD, Richard Keen MD and Rachel Lombardo MD | ||
| Sarah M. | 35-year-old woman with severe obesity, type 2 diabetes, polycystic ovary syndrome (PCOS), fatty liver disease, knee osteoarthritis, and bipolar disorder complicated by antipsych... | case | Orakle LLC | Nada Amgad, MD and Reham El Nahrawy PharmD | ||
| Mr Andre | A patient with non-small cell lung cancer (NSCLC) returns with new-onset fatigue and dark-colored urine. | case | Orakle LLC | Angioletta Lasagna MD and Paolo Sacchi MD | ||
| Timothy J. | A late preterm presents with respiratory distress and skeletal abnormalities. 0.50 AMA PRA Category 1 Credit(s)™. | case | Alexion, AstraZeneca Rare Disease | Raja Padidela MD | ||
| Lucy T. | A young girl presents with developmental regression. 0.50 AMA PRA Category 1 Credit(s)™. | case | Zevra Therapeutics | Tarekegn Hiwot MD and Al-Hertani Niemann MD | ||
| George R. | A 34-year-old with treatment-resistant psychosis and progressive gait instability. 0.50 AMA PRA Category 1 Credit(s)™. | case | Zevra Therapeutics | Tarekegn Hiwot MD and Al-Hertani Niemann MD | ||
| Antonia R. | A 62-year-old woman, presents with chronic pain, fatigue, and worsening depression. 0.50 AMA PRA Category 1 Credit(s)™. | case | Alexion, AstraZeneca Rare Disease | Steven Petak MD, Richard Keen MD and Rachel Lombardo MD | ||
| Cassandra A. | A 47-year-old patient with uncontrolled type 2 diabetes mellitus (T2DM) on 2 oral agents. | case | Orakle LLC | Lyle Mitzner, MD | ||
| Eva K. | A 28-year-old woman with psoriasis and psoriatic arthritis. | case | Orakle LLC | Marjorie E. Montanez-Wiscovich, MD, PhD, FAAD | ||
| Maria D. | Renal cell carcinoma (mRCC), initially treated with nephrectomy, now presents with a persistent cough. | case | Orakle LLC | Sahil D. Doshi MD | ||
| Jane T. | Relapsing neurological symptoms in a 51-year-old female | case | UCB | Tania A Reyna, MD, MSCS, FAAN | ||
| Andrew T. | A 55-year-old man with CI-DME and fluctuating response to anti-VEGF monotherapy | case | Orakle LLC | Marc de Smet MD and Daniele Veritti MD | ||
| Chloe B. | Chloe presents with decreased urine output, vomiting, malaise, and shortness of breath | case | Alexion, AstraZeneca Rare Disease | Bernat Herrera Gomez, MD | ||
| Sophia M. | Seeking oral contraception and cycle regulation with a history of VTE and prior intolerance to a progestin-only pill. | case | Orakle LLC | Nada Amgad MD, Reham El Nahrawy PharmD and August Felix MBBS | ||
| Hana T | Painless bilateral vision loss in a patient with a history of age-related macular degeneration. | case | Orakle LLC | Zujaja Tauqeer MD, DPhil | ||
| Ichika H. | A 76-year-old woman with NSCLC and disease progression | case | Merck KGaA | Terufumi Kato MD | ||
| Mario Z. | A 69-year-old male with haematuria | case | medac GmbH | Jørgen Bjerggaard Jensen MD | ||
| Sabrina A. | Abdominal pain, nausea, decreased appetite and abdominal distension in a 45-year-old woman | case | CSL Behring | Vicente Arroyo MD, Mauro Bernardi MD, Paolo Angeli MD | ||
| Samuel D. | A 28-year-old male presenting with gross haematuria and foamy urine. | case | STADA AG | Jonathan Barratt, MD | ||
| Tessa V. | A woman presents with worsening shortness of breath on exertion | case | Orakle LLC | Anjali Owens, MD | ||
| Jean T. | A 68-year-old woman with locally advanced cutaneous squamous cell carcinoma | case | Orakle LLC | Guilherme Rabinowits MD and Ralf Gutzmer MD | ||
| Patricia C. | A 71-year-old woman presents to the ophthalmology department with visual deterioration following cataract surgery | case | Orakle LLC | Marc de Smet MD | ||
| Beryl H. | A woman presents to the emergency department one month ago, after sustaining a fall at home. | case | Orakle LLC | Serge Ferrari, MD | ||
| Karl Z. | A 35-year-old man with fatigue, muscle weakness and breathing discomfort | case | Sanofi Genzyme | Jordi Díaz-Manera, MD, Cristina Domínguez González MD, and Dr. Federica Deodato, MD | ||
| Tina D. | A 60-year-old woman with a history of simultaneous pancreas-kidney transplant and subsequent living-donor kidney transplant presents with new-onset BK viremia. | case | Verici Dx | Javeed Ansari, MD | ||
| Dawn K | A 44-year-old woman with relapsed diffuse large B-cell lymphoma (DLBCL) is to begin stem cell mobilization before planned autologous stem cell transplantation (ASCT). | case | Orakle LLC | Ann S. LaCasce, MD, MMSc | ||
| Matt P. | A man with ESRD due to diabetes and hypertension experiences delayed graft function after a kidney transplant. | case | Verici Dx | Zahraa Hajjiri, MD | ||
| Steven A. | Persistent symptoms in a 68-year-old man with polycythemia vera (PV) despite ongoing phlebotomy and escalating hydroxyurea therapy. | case | Orakle LLC | Ghaith Abu-Zeinah, MD and Claire Harrison, MD | ||
| Amos C. | A patient with Crohn’s disease presents with an asymptomatic recurrence. | case | Orakle LLC | Benjamin Cohen, MD and Carlos Taxonera, MD | ||
| Sonia A. | A 65-year-old woman with a history of invasive ductal carcinoma of the left breast presented with a left supraclavicular recurrence after 10 years. | case | Orakle LLC | Nour Abuhadra, MD | ||
| Katherine L. | A 63-year-old woman with newly diagnosed DLBCL | case | Hoffmann-La Roche | Nicholas Forward, MD | ||
| Rhonda Y. | Persistent right shoulder pain and limited progress in rehabilitation three months after open reduction and internal fixation for a proximal humeral fracture, despite prior anal... | case | Orakle LLC | Takahiro Machida, MD, PhD | ||
| Bridget W. | Persistent hyperglycemia despite insulin therapy. | case | Orakle LLC | Nada Amgad MD, Reham El Nahrawy PharmD and August Felix MBBS | ||
| Marcel O. | A routine employment checkup detected abnormal urinalysis. | case | Orakle LLC | Francesco Locatelli, MD, and Abraham W. Aron, MD | ||
| Sonia C. | A 56-year-old woman with end-stage renal disease presents to the emergency department with 2 days of fever and a painful rash affecting both hands. | case | Orakle LLC | George R Thompson MD and Divisha Sharma MD | ||
| Gordan J. | A 48-year-old man with chronic pancreatitis and severe malabsorption is experiencing progressive weight loss. | case | Orakle LLC | Abby Michaels, MS, RDN, CNSC | ||
| Tracy W. | A 74-year-old woman with chronic heart failure and persistent fatigue. | case | Orakle LLC | Nada Amgad MD, Reham El Nahrawy PharmD and August Felix MBBS | ||
| Joel H. | A 2-year-old boy presented with prolonged oral bleeding after trauma, with a history of excessive bleeding from immunization sites and no known family history of bleeding disord... | case | Orakle LLC | Hina A. Sheikh, MD and Franklin Bontempo, MD | ||
| Nona G. | A 46-year-old woman presented with a 15-year history of progressive numbness, weakness, and gait impairment. | case | Orakle LLC | August Felix MBBS | ||
| Cindy R. | A 7-year-old girl with scattered hyperpigmented skin lesions and a deep-seated mass. | case | Orakle LLC | Angela Hirbe, MD, PhD | ||
| Frank T. | An elderly man presenting with a 2-month history of progressive fatigue during routine daily activities. | case | Orakle LLC | Dr Mark J. Koury MD | ||
| Antony D. | A dialysis-dependent man in his 70s with recurrent Sweet syndrome-like flares over 2 years, responsive to corticosteroids but relapsing with taper. | case | Orakle LLC | Dr Mark J. Koury MD | ||
| Michael T. | A 34-year-old male with a radiologically and histologically confirmed diffuse-type tenosynovial giant cell tumor. | case | Orakle LLC | Albiruni Razak, MD | ||
| Stewart O. | A 46-year-old male with metastatic colorectal cancer and unresectable liver metastases. | case | Orakle LLC | Andrew S. Kennedy, MD, FACRO | ||
| Emanuella S. | A 50-year-old with recurrent cervical cancer presenting with a persistent cough. | case | Orakle LLC | Bogani Giorgio, MD | ||
| Caroline C. | A 50-year-old woman with relapsed multiple myeloma (MM) and high-risk cytogenetics presents with worsening fatigue, bone pain, and biochemical evidence of disease progression de... | case | Orakle LLC | Sascha A. Tuchman, MD | ||
| Jane O. | A 56-year-old woman with metastatic pancreatic adenocarcinoma and a newly diagnosed isolated distal DV | case | Orakle LLC | Nada Amgad MD, Reham El Nahrawy PharmD and August Felix MBBS | ||
| Lucy K. | A 59-year-old woman presents asymptomatically after a routine screening mammogram detected an abnormality. | case | Orakle LLC | Adam Brufsky, MD | ||
| Levi F. | A 49-year-old man with recurrent Candida glabrata graft infection. | case | Orakle LLC | Matteo Bassetti, MD PhD | ||
| Tolga C | A 68-year-old male with complaints of burning and tingling in both his feet that has been increasing in severity over the past 9 months. | case | Orakle LLC | Nada Amgad, MD, August Felix MBBS, Reham El Nahrawy PharmD | ||
| Spencer B. | A 64-year-old male with ESKD on hemodialysis, experiencing fatigue, low energy, poor sleep, and cold intolerance | case | Orakle LLC | F Locatelli MD, MJ Koury MD and S Bhandari MD | ||
| John D. | A 72-year-old male with high-grade urothelial carcinoma underwent transurethral resection of bladder tumor (TURBT) and intravesical Bacillus Calmette-Guérin (BCG) therapy but ex... | case | Orakle LLC | E Stavropoulou, MD | ||
| Mark L. | A 71-year-old man with a 4-month history of fatigue and recurrent upper respiratory infections. | case | Orakle LLC | Nada Amgad MD, Reham El Nahrawy PharmD and August Felix MBBS | ||
| Becky B. | A 7‐year‐old girl presented with recurrent self‐limiting epistaxis. | case | Orakle LLC | Nada Amgad MD, Reham El Nahrawy PharmD and August Felix MBBS |